Using genetically modified E. coli, the team managed to convert the components of plastic bottles into terephthalic acid, the active ingredient in paracetamol, in just 24 hours. The study was published in the scientific journal Nature Chemistry (NatChem).
The specialists used a fermentation process similar to that used in brewing beer. It occurs at room temperature and is virtually carbon-free, making it a more environmentally friendly alternative to modern drug production. gazeta.ru.
About 90% of the product produced by the reaction of terephthalic acid with genetically reprogrammed E. coli was paracetamol.
The technology is relevant for processing polyethylene terephthalate (PET), a plastic used in bottles and packaging. Every year, more than 350 million tons of such waste are generated worldwide, most of which end up in landfills or in the oceans.
Scientists continue to improve the technology to prepare it for industrial use.
